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miércoles, 22 de abril de 2015

Margaret G. Spinelli

Dear friends,

This week, I would like to change our work method and give the responsibility of diagnosis to all you. I hope you enjoy playing doctors!

I present you Mrs. A, a 34-year-old married mother. I want you to read down her story, which was studied by Margaret G. Spinelli, and write a clinical comment.

You could name her symptoms one by one and, considering her particular context, find out a diagnosis. If you can add more information about it etiology, management or treatment don’t be shy and explain us, it will be really interesting!

I am going to analyze this case in detail in my conclusion so don’t forget to come back in four or five days to check your answers.

Good luck and have fun, doctors!


María Lamana Villegas



Mrs. A, a 34-year-old married mother who lived with her husband and their 5-year-old daughter, strangled her infant son to death 3 weeks after birth. She had a planned, healthy pregnancy with some depression at 28 weeks’ gestation. She had a normal spontaneous vaginal delivery, giving birth to a healthy boy, “B.” She began breastfeeding immediately. From postpartum days 2 through 11, her depression worsened. She was unable to sleep but could not get out of bed or attend to her hygiene. She was suspicious that her husband would harm B. On postpartum day 2, she began having obsessional, ego-dystonic images of throwing B out the window. She believed, despite the pediatrician’s reassurances, that she was harming B with her breast milk and that he was losing weight. She was unable to give him a bath, believing that he had “gas” or “something bad” inside and could not be moved.
On day 12, while alone in the car with B, she thought of killing herself and the baby, although “at the time I don’t think I had any idea why.” On day 13, she attempted suicide by overdose. She slept through the night and did not report the suicide attempt to anyone. She abruptly weaned B and then became disorganized and confused, unsure of what formula and size and types of bottles and nipples to use. She was agitated, calling friends day and night for opinions. On day 15 she attempted to smother B with a towel. “I don’t believe it was a thought,” she said. “It was ‘autopilot.’” Her husband came upstairs, and Mrs. A believes that his presence shook her out of the “state” she was in. “I did not have the compulsion to hurt him any more after that evening … I just thought something was wrong, and I wasn’t thinking straight.” Her husband knew that she was not herself, but he did not understand that she was depressed and psychotic. Mrs. A did not receive treatment for her illness.
On postpartum day 20, Mrs. A awoke at 6:30 a.m. to feed B when he cried. Her husband and daughter kissed her goodbye, and Mr. A walked their daughter to school before going to work. She soon felt as if she was “taken over.” She describes a dazed, trance-like state with confusion: “Something internal like a force … it was not a voice … but I did not have control. It was an instant. I don’t recall thinking anything … I had no feelings. It was happening but I wasn’t there.… At the time, nothing came into my head saying, ‘No, do not do this.’ … My inside was gone and it was something else.” She briefly placed a towel over B’s nose and mouth, but stopped. The “force” then became intense. She placed a washcloth in B’s mouth and then strangled him with a telephone cord. She felt she was not connected to her own hands. When B was dead, she washed him with a cloth, removed the remnants of his umbilical cord, changed his diaper, and left the room. She went into the bathroom, where she made an unsuccessful attempt to cut her wrists.
Mrs. A was charged with homicide and was incarcerated. She described her psychiatric history as “moody” with cycling states, every 3 days, of jocularity, creativity, and high energy alternating with an irritable, withdrawn mood and tearfulness. She had two previous episodes of major depression, including a postpartum depression after the birth of her daughter that was associated with ego-dystonic images of throwing her daughter against a wall or hitting her with a hammer. She denied psychotic thoughts. The depression resolved in 6 months without treatment. She was a successful “supermom” with her daughter and was an energetic worker in her job.
Mrs. A’s mother has a diagnosis of bipolar disorder, which worsened after the birth her second child. She had multiple psychiatric hospitalizations for psychotic episodes with chronic paranoia and grandiose, volatile moods.





martes, 7 de abril de 2015

PREVENTION OF COGNITIVE DECLINE

Hi everybody! 

Although it seems obvious that healthy habits prevent from several disorders, I think it is interesting to find out evidence with clinical trials. That' s why I have chosen this article. After reading it, some questions came to my mind: Why is it so hard for most people to follow healthy habits, even knowing their benefits? Should the Government fund healthy diets and gym classes instead of drugs? Could a pill substitutes the whole benefit from healthy lifestyle? 

You can give your opinion about those questions or comment anything else, it's up to you. Enjoy it ;)



Mental and physical exercises may protect against cognitive decline in the elderly 



add your  featured

The results of the first ever randomized controlled trial investigating a comprehensive program to slow cognitive decline among older people have been published in The Lancet.
older man on treadmill and doctor
The intervention included muscle and cardiovascular training, mental exercises and advice on how to manage metabolic and vascular risk factors.
Earlier today, Medical News Today reported on the results of a study published in the journal Neurologythat suggested physical activity may protect seniors from the effects of brain damage on motor function.
That study, conducted by researchers at Rush University Medical Center in Chicago, IL, found that the most active participants were unaffected by greater volumes of "white matter hyperintensities" - small areas of damage found in the brains of older people that are associated with impaired motor functioning.
In the study published in The Lancet, researchers from Sweden and Finland examined the effects on brain function of an intervention addressing assorted risk factors for age-related dementia.
These important risk factors included high body mass index (BMI) and heart health, and the intervention included healthy eating guidance, exercise, brain training and management of metabolic and vascular risk factors.
From across Finland, 1,260 participants aged between 60 and 77 were recruited for the study. Based on scores of standardized tests, all of the participants were considered to be at risk of dementia. Half were randomized into the intervention group and half formed a control group.

Intervention included regular meetings with health professionals over 2 years

Those in the intervention group participated in regular meetings over 2 years with health professionals, where participants were provided with "comprehensive advice" on maintaining a healthy diet, muscle and cardiovascular training, mental exercises and how to use blood tests and other means to manage metabolic and vascular risk factors.
At the conclusion of this 2-year study period, the researchers used the standardized Neuropsychological Test Battery to assess participants' mental function. They found that, overall, the intervention group scored an average of 25% higher on this test than the control group - a higher score corresponds to better mental functioning.
Breaking down the test's various components, the team also found that the intervention group scored 83% higher than the control group on ability to organize and regulate thought processes (executive functioning) and 150% higher on processing speed.
The participants will be followed for at least a further 7 years to establish whether the reduction in cognitive decline demonstrated by the intervention group is followed by a reduction in diagnoses of dementia and Alzheimer's disease.
"Much previous research has shown that there are links between cognitive decline in older people and factors such as diet, heart health and fitness," says lead author Prof. Miia Kivipelto, from the Karolinska Institutet in Stockholm, Sweden.
"However," Prof. Kivipelto adds, "our study is the first large randomized controlled trial to show that an intensive program aimed at addressing these risk factors might be able to prevent cognitive decline in elderly people who are at risk of dementia."
Last month, MNT looked at a study published in the journal Frontiers in Psychology that suggested meditation may reduce brain aging.
Written by 

Copyright: Medical News Today

Nisha Lal

Mental and physical exercises may protect against cognitive decline in the elderly

Cardiovascula
The results of the first ever randomized controlled trial investigating a comprehensive program to slow cognitive decline among older people have been published in The Lancet.
older man on treadmill and doctor
The intervention included muscle and cardiovascular training, mental exercises and advice on how to manage metabolic and vascular risk factors.
Earlier today, Medical News Today reported on the results of a study published in the journal Neurologythat suggested physical activity may protect seniors from the effects of brain damage on motor function.
That study, conducted by researchers at Rush University Medical Center in Chicago, IL, found that the most active participants were unaffected by greater volumes of "white matter hyperintensities" - small areas of damage found in the brains of older people that are associated with impaired motor functioning.
In the study published in The Lancet, researchers from Sweden and Finland examined the effects on brain function of an intervention addressing assorted risk factors for age-related dementia.
These important risk factors included high body mass index (BMI) and heart health, and the intervention included healthy eating guidance, exercise, brain training and management of metabolic and vascular risk factors.
From across Finland, 1,260 participants aged between 60 and 77 were recruited for the study. Based on scores of standardized tests, all of the participants were considered to be at risk of dementia. Half were randomized into the intervention group and half formed a control group.

Intervention included regular meetings with health professionals over 2 years

Those in the intervention group participated in regular meetings over 2 years with health professionals, where participants were provided with "comprehensive advice" on maintaining a healthy diet, muscle and cardiovascular training, mental exercises and how to use blood tests and other means to manage metabolic and vascular risk factors.
At the conclusion of this 2-year study period, the researchers used the standardized Neuropsychological Test Battery to assess participants' mental function. They found that, overall, the intervention group scored an average of 25% higher on this test than the control group - a higher score corresponds to better mental functioning.
Breaking down the test's various components, the team also found that the intervention group scored 83% higher than the control group on ability to organize and regulate thought processes (executive functioning) and 150% higher on processing speed.
The participants will be followed for at least a further 7 years to establish whether the reduction in cognitive decline demonstrated by the intervention group is followed by a reduction in diagnoses of dementia and Alzheimer's disease.
"Much previous research has shown that there are links between cognitive decline in older people and factors such as diet, heart health and fitness," says lead author Prof. Miia Kivipelto, from the Karolinska Institutet in Stockholm, Sweden.
"However," Prof. Kivipelto adds, "our study is the first large randomized controlled trial to show that an intensive program aimed at addressing these risk factors might be able to prevent cognitive decline in elderly people who are at risk of dementia."
Last month, MNT looked at a study published in the journal Frontiers in Psychology that suggested meditation may reduce brain aging.
Written by 

Copyright: Medical News Today
Not to be reproduced without permission